Victor L. Roberts, MD, has led as founding president and CEO of Endocrine Associates of Florida for 30 years. Also a member of the American College of Endocrinology and the American Diabetes Association, Victor L. Roberts, MD, comes to his work with a detailed and current knowledge of the conditions he treats. Although scientists have long since established excess weight as a risk factor for diabetes, little research has been done to determine if any particular types of fat deposits are more dangerous than others. Now, however, a study out of the United Kingdom and United States has suggested that a particular variant of the fat storage gene KLF14 may impact fat storage as well as level of diabetes risk. The team found a variation of the KLF14 gene that predisposed women to store excess fat around the hips rather than in the abdominal region. Not only were fat cells smaller in women with this variant, but the risk of diabetes was significantly lower. The other variant of the gene, which prompts fat storage in the abdomen, leads to much larger and fuller fat cells. Many of these cells demonstrate insufficiency of fat storage and are thus more likely to place the patient at risk for diabetes. The research team found that this trend applied only to female patients, and only to those who inherited the more risky gene variant from the maternal line. For these women, diabetes risk increased approximately 30 percent over the average. Researchers believe that these findings may be effective in understanding disease development, while potentially contributing to new treatments as personalized medicine advances.
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AuthorDr. Victor Roberts Archives
September 2021
CategoriesAll Community Outreach Covid-19 Cushing’s Syndrome Diabetes Health Hormonal Causes Hypothyroidism Urination Victor L Roberts MD |